Most Commons in Hematology
- Iron Deficiency Anemia - most common cause of anemia
- Anemia of Chronic Disease - most common cause of normocytic anemia
- Glucose-6-Phosphate Dehydrogenase Deficiency - most common RBC enzyme defect
- More common in males
- Highest frequency among Mediterranean regions, Africa, and China
- Most commonly seen in tropical geographic areas prevalent for malaria
- G6PD “A-” is the most common variant
- Sickle Cell SS disease - most common and most severe of the sickle cell disorders
- Warm-antibody AIHA (autoimmune hemolytic anemia) - most common of all AIHA
- Immune Hemolytic Anemia - commonly DRUG related
- Idiopathic Thrombocytopenic Purpura (ITP)
- Acute ITP - most common in children, preceded by viral illness, self-limiting
- Chronic ITP - most common in adult women (20-40), idiopathic, not self-limiting
- Thrombotic Thrombocytopenic Purpura (TTP)
- Most commonly acquired due to an inhibitory antibody that blocks ADAMTS 13 activity
- Hemophilia A and B - most common in males
- X-linked recessive bleeding disorders
